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Licorice

Licorice

 

Licorice

Licorice or sweet root is obtained from Glycyrrhiza glabra, a legume related to beans and peas that is native to southern Europe and parts of Asia. Licorice gained attention of our ancestors due to its remarkable sweetening effect which may account upto 30 to 50 times of sugar. In ancient times, licorice was used by Egyptians as a beverage and a pharmaceutical.

Botanical name: Glycyrrhiza glabra

Family: Fabaceae

Part Used: Roots and stems

Active Ingredient: Glycyrrhizin, Glabridin, glycyrrhetinic acid

Testing Method: HPLC

 
Licorice Brochure download
Licorice Brochure  

The plant contains various substances with different mechanisms of action: Saponins found in the herb act both as mucus thinning and expectorant, antiviral action is exhibited by glycyrrhizin, and bacteria growth inhibitory effect is exhibited by isoflavonoids hispaglabridin A and B and glabridin. Glycyrrhizic acid has an antispasmodic effect on the gastrointestinal tract, whereby the bacteria in the intestine convert licorice into a substance that acts as a liver-protective agent by neutralizing free radicals.

The licorice extract manufactured at Hindustan Herbal Limited (HHL) is of premium quality; supported by the fact that extraction is purely water based and quality raw material is obtained from reliable sources in Central Asia and Middle East. To safeguard against any deviation in quality, we maintain an inventory that can last for 20-24 months.

 

Licorice
   Licorice
Extraction of Licorice
Licorice Extraction
Types of industries using LICORICE and its derivatives
Licorice    Licorice Plant
Pharmacological Action Mechanism of action Application
Anti-Inflammatory
  • Reactive Oxygen Species (ROS)
  • Certain enzymes which are responsible for inflammatory
  • Arthritis
  • Allergic Disorders
Anti-Oxidant
  • Facilitates free radical scavenging
  • Chelates metal ion
  • Inhibits Lipid peroxidation
  • Skin care products
  • Cosmetics
  • Hair care products
Healing of Skin Disorders
  • the associated inflammation
  • the symptoms such as redness, rashes, itching and swelling associated with the skin disorders
  • Eczema (Atopic Dermatitis)
  • Skin Rashes
  • Psoriasis
  • Itchy & Dry Skin
Respiratory Problems
  • Acts as a good expectorant
  • Breaks up and facilitate secretion of phlegm
  • Widens the air passage
  • Asthma
  • Chest pain/ Cold
  • Emphysema
  • Sore throat
Digestive Disorders
  • Can inhibit the growth of toxic bacteria such as H. pylori
  • Dyspepsia
  • Gastric ulcer
  • Stomach Distress
  • Bloating
  • Indigestion
Aids in Weight loss
  • Increases the levels of PPAR-alpha, stimulates breakdown of fats
  • Decreases levels of SREBP-1 protein which promotes production of fats
  • Modulates glucose metabolism by activation of AMPK
  • Weight management
Pre-menstrual & Menstrual Syndrome /Menopause
  • Estrogenic action helps in hot flashes, mood swings, breast tenderness, menstrual cramps, nausea & bloating
  • Anti-spasmodic & Anti-inflammatory action
  • Pre-menstrual Syndrome
  • Menstrual cramps
  • Bloating
Promotes Oral Health
  • Anti-bacterial action
  • Anti-microbial action
  • Reduces cavity causing bacteria, reduces plague & fights bad breath
  • Keeps the teeth & gums healthy
  • Bleeding gums
  • Bad breath
  • Plague
Anti-viral & anti-bacterial
  • Promotes activation of interferon
  • Promotes multiplication of immune system killer T-cells
  • HIV
Boosts Liver Health
  • Regulates the level of AST and ALT
  • Regulates the level of hepatic oxidative species
  • Alcohol Induced Fatty Liver
  • Jaundice
Boosts Brain Health
  • Reduces stress
  • Slow down brain ageing & have positive effect on brain cells
  • Keep mental skills sharp
  • Anti-depressant
  • Brain Tonic
Our Variants available

  1. Licorice extract
  2. De-Glycyrrhizinated Licorice (DGL)
  3. Monoammonium Glycyrrhizinate [ EP/USP]
  4. Enoxolone (EP)
  5. Dipotassium Glycyrrhizinate
  6. Stearyl Glycyrrhetinate
  7. Glabridin
  8. Glycyrrhizinic acid Upto 90%

References

  1. Wang, L., Yang, R., Yuan, B., Liu, Y., & Liu, C. (2015). The antiviral and antimicrobial activities of licorice, a widely-used Chinese herb. Acta Pharmaceutica Sinica. B, 5(4), 310–315. http://doi.org/10.1016/j.apsb.2015.05.005

  2. Rahnama, M., Mehrabani, D., Japoni, S., Edjtehadi, M., & Saberi Firoozi, M. (2013). The healing effect of licorice (Glycyrrhiza glabra) on Helicobacter pylori infected peptic ulcers. Journal of Research in Medical Sciences : The Official Journal of Isfahan University of Medical Sciences, 18(6), 532–533. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3818629/

  3. Rao, K. V. S. (1993). A REVIEW ON LICORICE. Ancient Science of Life, 13(1-2), 57–88. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3336539/

  4. Huang, Q.-C., Wang, M.-J., Chen, X.-M., Yu, W.-L., Chu, Y.-L., He, X.-H., & Huang, R.-Y. (2016). Can active components of licorice, glycyrrhizin and glycyrrhetinic acid, lick rheumatoid arthritis? Oncotarget, 7(2), 1193–1202. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811453/

  5. Saeedi M, Morteza-Semnani K, Ghoreishi MR. The treatment of atopic dermatitis with licorice gel. J Dermatolog Treat. 2003 Sep;14(3):153-7. https://www.ncbi.nlm.nih.gov/pubmed/14522625

  6. Yu JY, Ha JY, Kim KM, Jung YS, Jung JC, Oh S. Anti-Inflammatory activities of licorice extract and its active compounds, glycyrrhizic acid, liquiritin and liquiritigenin, in BV2 cells and mice liver. Molecules. 2015 Jul 20;20(7):13041-54. https://www.ncbi.nlm.nih.gov/pubmed/26205049

  7. Kobayashi S, Miyamoto T, Kimura I, Kimura M. Inhibitory effect of isoliquiritin, a compound in licorice root, on angiogenesis in vivo and tube formation in vitro. Biol Pharm Bull. 1995 Oct;18(10):1382-6. https://www.ncbi.nlm.nih.gov/pubmed/8593441

  8. Ju SM, Kim MS, Jo YS, Jeon YM, Bae JS, Pae HO, Jeon BH. Licorice and its active compound glycyrrhizic acid ameliorates cisplatin-induced nephrotoxicity through inactivation of p53 by scavenging ROS and overexpression of p21 in human renal proximal tubular epithelial cells. Eur Rev Med Pharmacol Sci. 2017 Feb;21(4):890-899. https://www.ncbi.nlm.nih.gov/pubmed/28272690

  9. Yang R, Yuan BC, Ma YS, Zhou S, Liu Y. The anti-inflammatory activity of licorice, a widely used Chinese herb. Pharm Biol. 2017 Dec;55(1):5-18. Epub 2016 Sep 21. https://www.ncbi.nlm.nih.gov/pubmed/27650551

  10. Nourazarian SM, Nourazarian A, Majidinia M, Roshaniasl E. Effect of Root Extracts of Medicinal Herb Glycyrrhiza glabra on HSP90 Gene Expression and Apoptosis in the HT-29 Colon Cancer Cell Line. Asian Pac J Cancer Prev. 2015;16(18):8563-6. https://www.ncbi.nlm.nih.gov/pubmed/26745117